MicroRNA-146a Prevents AAA Development Through Repressing VSMC Inflammation
MiR-146a prevents AAA formation and progression by maintaining VSMC homeostasis in the proinflammatory microenvironment. Upregulation of miR-146a in the aortas shows great potential as a new therapeutic strategy to limit AAA expansion and progression.
Authors
- Rong Qi (ORCID: https://orcid.org/0000-0002-0627-9968)
- Zeyu Cai (ORCID: https://orcid.org/0000-0003-3664-9189)
- Yu‐Tsung Shih (ORCID: https://orcid.org/0000-0002-5277-533X)
- Weipeng Hu (ORCID: https://orcid.org/0000-0001-5318-0808)
- Haoyue Ma (ORCID: https://orcid.org/0000-0002-0529-5368)
- Qingyi Zhang (ORCID: https://orcid.org/0000-0002-2328-1453)
- Yi-Ju Ko
- Jeng‐Jiann Chiu (ORCID: https://orcid.org/0000-0003-4071-7367)
- Qinyu Wang (ORCID: https://orcid.org/0009-0009-5704-135X)
- Chih-I Lee
Institutions
- National Health Research Institutes (TW)
- Peking University (CN)
- National Tsing Hua University (TW)
- National Health and Family Planning Commission (CN)
- Taipei Medical University (TW)
Publication Details
- Journal
- Hypertension
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1161/hypertensionaha.125.25133
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00