Clara cell secretory protein 16 protects against PM2.5-induced ferroptosis in mouse lung epithelial cells in a concentration-dependent manner

CC16 effectively mitigates PM2.5-induced cellular injury in mouse pulmonary epithelial cells through inhibition of ferroptosis, with its protective effect showing a clear concentration dependence. These findings suggest CC16 as a novel strategy for PM2.5-induced respiratory disease.

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Publication Details

Journal
American Journal of Translational Research
Published
2025-01-01
DOI
https://doi.org/10.62347/ozzv2763
Primary Topic
Ferroptosis and cancer prognosis
Type
article
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article

Clara cell secretory protein 16 protects against PM2.5-induced ferroptosis in mouse lung epithelial cells in a concentration-dependent manner

Aili Wang
American Journal of Translational Research
Ferroptosis and cancer prognosis
article

Clara cell secretory protein 16 protects against PM2.5-induced ferroptosis in mouse lung epithelial cells in a concentration-dependent manner

Aili Wang
article en

Abstract

CC16 effectively mitigates PM2.5-induced cellular injury in mouse pulmonary epithelial cells through inhibition of ferroptosis, with its protective effect showing a clear concentration dependence. These findings suggest CC16 as a novel strategy for PM2.5-induced respiratory disease.

American Journal of Translational ResearchVol. 17(10)
Wuhan Pulmonary Hospital (CN), Wuhan No.9 Hospital (CN)
Openalex Percentile: Top 55%
Ferroptosis and cancer prognosis
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