Early continuous blood purification and timely liver transplantation in a neonatal-onset ornithine transcarbamylase deficiency: a case report
This case highlights the importance of early diagnosis and intervention in neonatal-onset OTCD. Timely application of continuous blood purification (CBP) followed by liver transplantation resulted in significant improvements in both metabolic control and neurodevelopment.
Authors
- Xiaolu Ma (ORCID: https://orcid.org/0000-0001-9514-6042)
- X. Ju (ORCID: https://orcid.org/0000-0002-9745-1638)
- Ziming Zhang (ORCID: https://orcid.org/0000-0002-8307-2717)
- Tian Xie (ORCID: https://orcid.org/0000-0002-5445-664X)
- Zhigang Gao (ORCID: https://orcid.org/0000-0001-7727-3072)
- Zheng Chen (ORCID: https://orcid.org/0000-0002-0261-8061)
- Liping Shi
- Dandan Pan (ORCID: https://orcid.org/0000-0001-7404-5269)
Institutions
- Children's Hospital of Zhejiang University (CN)
- Zhejiang Lab (CN)
Publication Details
- Journal
- Translational Pediatrics
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/tp-2025-436
- Primary Topic
- Metabolism and Genetic Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00