A Multicenter Retrospective Analysis on Lymph Node Metastasis in Clinically Node-Negative (cN0) Patients with Small-Sized Breast Cancer
Small breast cancer with cN0 and low Ki-67 expression is associated with reduced but non-negligible nodal metastasis. These findings support caution in omitting axillary surgery and highlight the need for individualized risk stratification rather than universal omission.
Authors
- Xueqin Yan
- Zhen Zhu
- Tianfu Dong
- Yinjiao Fei (ORCID: https://orcid.org/0000-0003-3354-4082)
- Lu Wen (ORCID: https://orcid.org/0000-0002-1773-1876)
- Jian Zhang
- Dandan Wang (ORCID: https://orcid.org/0000-0002-1926-9128)
- Zhaohui Zhu (ORCID: https://orcid.org/0000-0001-9931-850X)
Institutions
- Xuzhou Medical College (CN)
- Second People’s Hospital of Huai’an (CN)
- The First People’s Hospital of Lianyungang (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Cancer Management and Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/cmar.s543923
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province