Pharmacokinetics and Safety of Clofazimine in Women With Rifampicin-resistant Tuberculosis During Pregnancy and the Postpartum Period: Results From IMPAACT P1026s
Overall, antepartum and postpartum clofazimine exposures were comparable to those reported in nonpregnant women with RR-TB. Exposures were lower than expected in the postpartum period, particularly compared with the third trimester of pregnancy.
Authors
- Kittipong Rungruengthanakit
- Amita Jain Gupta (ORCID: https://orcid.org/0000-0001-7036-2718)
- Marije Van Schalkwyk (ORCID: https://orcid.org/0000-0003-2679-901X)
- Tim Roy Cressey (ORCID: https://orcid.org/0000-0002-8106-0974)
- Emily Barr (ORCID: https://orcid.org/0000-0002-3578-3389)
- Anneke Catharina Hesseling (ORCID: https://orcid.org/0000-0001-9399-9834)
- Sandra K. Burchett (ORCID: https://orcid.org/0000-0002-7106-9262)
- Anthony J. Garcia‐Prats (ORCID: https://orcid.org/0000-0002-9280-1950)
- Ahizechukwu Chigoziem Eke (ORCID: https://orcid.org/0000-0002-0070-9840)
- Edmund V. Capparelli (ORCID: https://orcid.org/0000-0002-1630-0505)
- Alexander Benns
- James S. Ngocho (ORCID: https://orcid.org/0000-0001-6242-9863)
- Diane G. Costello (ORCID: https://orcid.org/0000-0002-6075-554X)
- David E. Shapiro (ORCID: https://orcid.org/0009-0008-6051-7745)
- Gonzague Jourdain (ORCID: https://orcid.org/0000-0002-3365-7020)
- Lubbe Wiesner (ORCID: https://orcid.org/0000-0002-9070-8699)
- Pooja Mehta
- Jennifer Hughes (ORCID: https://orcid.org/0000-0002-5349-9509)
- Régis Kreitchmann (ORCID: https://orcid.org/0000-0002-1146-0497)
- Francesca Aweeka (ORCID: https://orcid.org/0000-0002-6005-6124)
- Mauricio Pinilla
- Kevin Knowles
- Kristina M. Brooks (ORCID: https://orcid.org/0000-0002-3832-8699)
- Amy Gonzalez
- Nahida Chakhtoura
- Brookie M. Best (ORCID: https://orcid.org/0000-0001-8569-2293)
- Kathleen George
- Eric H. Decloedt (ORCID: https://orcid.org/0000-0003-1815-5150)
- Lee Fairlie (ORCID: https://orcid.org/0000-0001-5327-1734)
- Jiajia Wang (ORCID: https://orcid.org/0000-0001-8559-7501)
- Mary E. Smith
- Alice Marie Stek
- Renee Browning (ORCID: https://orcid.org/0000-0003-3839-9478)
- Mark Mirochnick
- Alicia Hernández
- Pra-ornsuda Sukrakanchana
- Adrie Bekker
- Flynn McMorrow
- Tara DeYampert
- Lisa M Frenkeland
- Chelsea Stotz
Institutions
- Boston University (US)
- University of Southern California (US)
- Family Health International 360 (US)
- National Institutes of Health (US)
- Desmond Tutu HIV Foundation (ZA)
- Johns Hopkins University (US)
- University of Cape Town (ZA)
- University of the Witwatersrand (ZA)
- Stellenbosch University (ZA)
- Johns Hopkins Medicine (US)
- Tygerberg Hospital (ZA)
- Moshi Co-operative University (TZ)
- Rady Children's Hospital-San Diego (US)
- Cancer Research And Biostatistics (US)
- National Institute of Allergy and Infectious Diseases (US)
- Frontier Science & Technology Research Foundation, Inc. (US)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (US)
- University of Colorado Anschutz Medical Campus (US)
- University of Montana (US)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1093/infdis/jiaf504
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00