Prognostic factors for overall survival in patients with early gastric cancer: a retrospective cohort study based on SEER database

Age, gender, race, the number of dissected lymph nodes, LNM, invasion depth, and tumor size are independent factors affecting the prognosis of EGC patients. There are also differences in risk factors affecting prognosis among different age groups and different gender groups. The optimal cut-off point for tumor size was 20 mm, which can exert a significant impact on the prognosis of EGC patients without LNM or those aged ≥60 years. These findings can provide guidance for clinical decision-making. Identifying high-risk patients with different clinical characteristics can offer certain evidence-based support for the precise treatment of patients with EGC, thereby improving the overall patient management.

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Publication Details

Journal
Journal of Gastrointestinal Oncology
Published
2025-10-01
DOI
https://doi.org/10.21037/jgo-2025-405
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
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article

Prognostic factors for overall survival in patients with early gastric cancer: a retrospective cohort study based on SEER database

Lei Cao, Peng Song, Yanhong Liu, Yongjie Zhao et al.
Journal of Gastrointestinal Oncology
Gastric Cancer Management and Outcomes
article

Prognostic factors for overall survival in patients with early gastric cancer: a retrospective cohort study based on SEER database

Lei Cao, Peng Song, Yanhong Liu, Yongjie Zhao, Jia Zhao, Chuntao Wang, Wencong Tian
article en

Abstract

Age, gender, race, the number of dissected lymph nodes, LNM, invasion depth, and tumor size are independent factors affecting the prognosis of EGC patients. There are also differences in risk factors affecting prognosis among different age groups and different gender groups. The optimal cut-off point for tumor size was 20 mm, which can exert a significant impact on the prognosis of EGC patients without LNM or those aged ≥60 years. These findings can provide guidance for clinical decision-making. Identifying high-risk patients with different clinical characteristics can offer certain evidence-based support for the precise treatment of patients with EGC, thereby improving the overall patient management.

Journal of Gastrointestinal OncologyVol. 16(5)
Tianjin First Center Hospital (CN), Tianjin Medical University General Hospital (CN), Tianjin Medical University (CN)
Openalex Percentile: Top 55%
Gastric Cancer Management and Outcomes
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Prognostic factors for overall survival in patients with early gastric cancer: a retrospective cohort study based on SEER database — Lei Cao, Peng Song, et al. · Journal of Gastrointestinal Oncology (2025) | TGRS Research Map | TGRS