ISM2 as a prognostic biomarker and mediator of immune infiltration in colorectal cancer: evidence from bioinformatics and experimental analysis
ISM2 is overexpressed in CRC and is associated with clinicopathological features, prognosis, and immune infiltration. It holds potential as a prognostic biomarker; however, further research is needed to elucidate its underlying mechanisms and clinical implications.
Authors
- Hai-Xiao Chen
- Ran Ji (ORCID: https://orcid.org/0000-0001-5797-0153)
- Wenan Qiang (ORCID: https://orcid.org/0000-0001-5068-7128)
- Ying Jiang (ORCID: https://orcid.org/0000-0003-0871-1360)
- Xiaoyun Yan (ORCID: https://orcid.org/0000-0003-2115-9013)
- Qing Zhang (ORCID: https://orcid.org/0000-0002-7504-0555)
- Dong-Sheng Zhao
- Jiaqi Ye (ORCID: https://orcid.org/0000-0002-5824-2518)
Institutions
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Journal of Gastrointestinal Oncology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/jgo-2025-295
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00