Serum immunoglobulin G glycosylation profiling in breast cancer using a 56-lectin microarray and subtype-specific patterns
By employing a broad 56-lectin microarray and subtype analysis, our results reveal distinct serum IgG glycosylation profiles associated with different BC molecular markers. These findings offer a novel framework for investigating disease pathogenesis and identifying candidate biomarkers for BC.
Authors
- Zhen Zhang (ORCID: https://orcid.org/0000-0002-7445-9442)
- Jialin Zhao (ORCID: https://orcid.org/0000-0001-6475-6673)
- Siting Li (ORCID: https://orcid.org/0000-0002-8292-1393)
- Peng Li (ORCID: https://orcid.org/0000-0003-3548-4589)
- Mingwei Ma
- Feng Mao (ORCID: https://orcid.org/0000-0003-0969-817X)
- Yanna Zhang (ORCID: https://orcid.org/0000-0002-7725-7176)
- Dachun Zhao (ORCID: https://orcid.org/0000-0003-2203-9259)
- Jingjing Meng (ORCID: https://orcid.org/0000-0001-7104-608X)
- Chaojun Hu
Institutions
- Sun Yat-sen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Fifth Affiliated Hospital of Zhengzhou University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Gland Surgery
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/gs-2025-298
- Primary Topic
- Glycosylation and Glycoproteins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00