Comprehensive bioinformatic analysis reveals sorafenib response-related prognostic signature in hepatocellular carcinoma

Our study established a sorafenib response-related prognostic risk prediction model in HCC based on five signature genes (<i>DNASE1L3</i>, <i>ACSL6</i>, <i>ACAN</i>, <i>BRSK1</i> and <i>CD68</i>), which had high predictive precision on sorafenib response.

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Publication Details

Journal
Journal of Gastrointestinal Oncology
Published
2025-10-01
DOI
https://doi.org/10.21037/jgo-2024-1020
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

Comprehensive bioinformatic analysis reveals sorafenib response-related prognostic signature in hepatocellular carcinoma

Guoshan Ding, Liang Wu, Liang Peng, Junfeng Dong et al.
Journal of Gastrointestinal Oncology
Hepatocellular Carcinoma Treatment and Prognosis
article

Comprehensive bioinformatic analysis reveals sorafenib response-related prognostic signature in hepatocellular carcinoma

Guoshan Ding, Liang Wu, Liang Peng, Junfeng Dong, Wenyuan Guo, Yuanyu Zhao, M C Yu, Han-Xiang Zhong
article en

Abstract

Our study established a sorafenib response-related prognostic risk prediction model in HCC based on five signature genes (<i>DNASE1L3</i>, <i>ACSL6</i>, <i>ACAN</i>, <i>BRSK1</i> and <i>CD68</i>), which had high predictive precision on sorafenib response.

Journal of Gastrointestinal OncologyVol. 16(5)
Shanghai Changzheng Hospital (CN)
Openalex Percentile: Top 58%
Hepatocellular Carcinoma Treatment and Prognosis
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