The effector AGLIP1 hijacks peroxidase OsAPX8 to coordinate rice immune suppression and ROS-Driven cell death for facilitating Rhizoctonia solani infection
Our findings uncover a novel virulence mechanism utilized by R. solani, where the effector AGLIP1 subverts host antioxidant defenses via OsAPX8 inhibition and mislocalization, facilitating pathogen infection. This insight highlights potential breeding targets, suggesting strategies to stabilize OsAPX8 function or prevent its subversion by AGLIP1 for developing rice cultivars with improved resistance to sheath blight.
Authors
- Zhuangyuan Fu
- Shubin Li
- Liyao Dong (ORCID: https://orcid.org/0000-0002-4842-713X)
- Jun Yang (ORCID: https://orcid.org/0000-0002-9401-3528)
- Wei Cheng (ORCID: https://orcid.org/0000-0001-5866-7236)
- Yufeng Jia
- Jiyang Wang (ORCID: https://orcid.org/0000-0003-4781-3829)
- Bing Cao (ORCID: https://orcid.org/0000-0002-0310-672X)
- Wenxin Jiang (ORCID: https://orcid.org/0009-0008-6315-3721)
- Junyi Ma
Institutions
- Shenyang Agricultural University (CN)
- Shandong Academy of Agricultural Sciences (CN)
- Sanya University (CN)
- China Agricultural University (CN)
- Hainan Tropical Ocean University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.jare.2025.10.063
- Primary Topic
- Plant Disease Resistance and Genetics
- Type
- article
- Field-Weighted Citation Impact
- 0.00