Plasma fibrinogen level and severe bleeding in cardiac surgery: an observational post hoc study of the ALBICS trial
The preoperative fibrinogen level had borderline and the post-CPB fibrinogen level had strong associations with severe bleeding and resternotomy in patients undergoing on-pump cardiac surgery. Further research is required to delineate whether the observed association represents a cause-and-effect relationship.
Authors
- Otto Helve (ORCID: https://orcid.org/0000-0001-6254-3180)
- Eero Pesonen (ORCID: https://orcid.org/0000-0001-9624-3063)
- Minna Ilmakunnas (ORCID: https://orcid.org/0000-0002-8469-4091)
- Raili Suojaranta
- Seppo Hiippala
- Liisa Petäjä
- Hanna Vlasov (ORCID: https://orcid.org/0000-0002-8770-1963)
- Peter Raivio (ORCID: https://orcid.org/0000-0001-6130-8242)
- Erika Wilkman (ORCID: https://orcid.org/0000-0003-4250-7523)
- Akseli Talvasto (ORCID: https://orcid.org/0000-0002-8451-3916)
- Tatu Juvonen
Institutions
- University of Helsinki (FI)
- Helsinki University Hospital (FI)
- Finnish Red Cross (FI)
- Finnish Institute for Health and Welfare (FI)
Publication Details
- Journal
- Canadian Journal of Anesthesia/Journal canadien d anesthésie
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1007/s12630-025-03046-7
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Foundation for Cardiovascular Research
- Sydäntutkimussäätiö