Assessment of temperature dynamics in pulsed field ablation with a variable-loop circular catheter: a comparative analysis of waveform configurations and irrigation rates in specimens of bovine ventricular myocardium
This study confirms that PFA can induce relevant thermal effects, especially at the tissue interface. However, waveform optimization and active cooling significantly mitigate these effects. Such strategies to minimize thermal effects should be implemented in clinical practice to enhance procedural safety.
Authors
- Thanassis Papaioannou
- Luigi Di Biase (ORCID: https://orcid.org/0000-0001-6508-4047)
- Carola Gianni (ORCID: https://orcid.org/0000-0002-8174-7207)
- Amin Al‐Ahmad (ORCID: https://orcid.org/0000-0002-8547-025X)
- Elio Zito
- MOUSSA C. MANSOUR (ORCID: https://orcid.org/0000-0003-3326-9973)
- Vivek Y. Reddy (ORCID: https://orcid.org/0000-0002-5638-4993)
- J. David Burkhardt (ORCID: https://orcid.org/0000-0003-1925-5241)
- Vincenzo Mirco La Fazia (ORCID: https://orcid.org/0000-0001-7548-4685)
- Tushar Sharma (ORCID: https://orcid.org/0000-0001-5857-4996)
- Andrea Natale
Institutions
- University of Rome Tor Vergata (IT)
- Albert Einstein College of Medicine (US)
- University of Milan (IT)
- Massachusetts General Hospital (US)
- St David's Medical Center (US)
- Scripps Clinic (US)
- Texas Cardiac Arrhythmia (US)
- MetroHealth Medical Center (US)
- Case Western Reserve University (US)
- Webster University (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- EP Europace
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1093/europace/euaf278
- Citations
- 3
- Primary Topic
- Cardiac Arrhythmias and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.16