Profound hematologic instability in consanguinity-associated familial hemophagocytic lymphohistiocytosis: a pediatric case report
This case underscores the diagnostic challenges and therapeutic complexities in managing FHL, particularly in the context of consanguinity and genetic predisposition. Advances in genetic testing and treatment modalities are critical for improving outcomes and long-term prognosis in FHL. Continued research is essential to refine diagnostic criteria and therapeutic strategies for optimal patient care.
Authors
- Muhammad Numan Awais
- Faiza Yousaf
- Muhammad Ahmad Qureshi (ORCID: https://orcid.org/0000-0003-3293-7079)
- Syed Faqeer Hussain Bokhari (ORCID: https://orcid.org/0000-0002-6937-9894)
- Danyal Bakht (ORCID: https://orcid.org/0009-0005-0466-5485)
- Rabia Yousaf
Institutions
- King Edward Medical University (PK)
- Jackson Memorial Hospital (US)
- Shifa International Hospital (PK)
- Mayo Hospital (PK)
- Shaheed Suhrawardy Medical College (BD)
Publication Details
- Journal
- Annals of Medicine and Surgery
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1097/ms9.0000000000004167
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00