Obinutuzumab for B-cell depletion prior to kidney transplant in a highly sensitized patient with anaphylactic reaction to rituximab
Desensitization strategies, including B-cell depletion with obinutuzumab, played a crucial role in achieving successful kidney transplantation in a highly sensitized patient. This case underscores the importance of personalized approaches and ongoing research aimed at overcoming immunological barriers to kidney transplantation.
Authors
- Miquel Lozano (ORCID: https://orcid.org/0000-0003-2593-833X)
- Thais Lizondo
- Sonia Gelis
- Paola Charry (ORCID: https://orcid.org/0000-0002-4777-9643)
- Dolors Soy (ORCID: https://orcid.org/0000-0001-8128-345X)
- Carla Bastida (ORCID: https://orcid.org/0000-0003-0845-8107)
- Ignacio Revuelta (ORCID: https://orcid.org/0000-0002-3584-4516)
- Inés Monge‐Escartín (ORCID: https://orcid.org/0000-0001-9959-9102)
- I. Carro
Institutions
- Hospital Clínic de Barcelona (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Kidney Centre (PK)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- American Journal of Health-System Pharmacy
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1093/ajhp/zxaf300
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00