Decoding Fibromyalgia: Genetic Insights into Gut and Immune System Interactions
This study highlights the role of gut microbiota and inflammatory proteins (cytokines/chemokines) in the pathogenesis of FM. Through Gene Ontology (GO) functional enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses, the findings suggest their involvement in immune regulation, inflammatory responses, and viral pathways. These findings provide new insights into potential therapeutic targets for modulating gut health and immune responses, opening new avenues for future research and clinical interventions.
Authors
- Mengqi Niu (ORCID: https://orcid.org/0000-0003-1201-2474)
- Michael H. J. Maes (ORCID: https://orcid.org/0000-0002-2012-871X)
- Victoria Sarafian (ORCID: https://orcid.org/0000-0003-1501-0175)
- Jing Li (ORCID: https://orcid.org/0009-0007-1333-7752)
Institutions
- Thai Red Cross Society (TH)
- University of Electronic Science and Technology of China (CN)
- Chulalongkorn University (TH)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Medical University Plovdiv (BG)
- King Chulalongkorn Memorial Hospital (TH)
- Kyung Hee University (KR)
Publication Details
- Journal
- Journal of Pain Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/jpr.s525610
- Primary Topic
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00