Variation in Maximal Doses of Vasopressors Used for Treatment of Shock in Intensive Care Units in Alberta Canada: A Retrospective Cohort Study

In Alberta CA, the maximum combined vasopressor dose for patients with shock varied between ICUs after adjustment for severity of illness. Some survival occurred even with high maximal doses. Further work is needed to understand the best approach to determining maximum doses for individual patients at high risk of death.

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Publication Details

Journal
Anesthesia & Analgesia
Published
2025-10-29
DOI
https://doi.org/10.1213/ane.0000000000007821
Citations
1
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.35
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article

Variation in Maximal Doses of Vasopressors Used for Treatment of Shock in Intensive Care Units in Alberta Canada: A Retrospective Cohort Study

Ruxandra Pinto, Martin Chapman, Allan J. Walkey, Bijan Teja et al.
1 citations
Anesthesia & Analgesia
Sepsis Diagnosis and Treatment
1.35
article

Variation in Maximal Doses of Vasopressors Used for Treatment of Shock in Intensive Care Units in Alberta Canada: A Retrospective Cohort Study

Ruxandra Pinto, Martin Chapman, Allan J. Walkey, Bijan Teja, Henry T. Stelfox, Lisa D. Burry, Hannah Wunsch, Nicholas A. Bosch, Damon C. Scales, Andrea D. Hill
article en
1 citations

Abstract

In Alberta CA, the maximum combined vasopressor dose for patients with shock varied between ICUs after adjustment for severity of illness. Some survival occurred even with high maximal doses. Further work is needed to understand the best approach to determining maximum doses for individual patients at high risk of death.

Anesthesia & Analgesia
Boston University (US), Mount Sinai Hospital (CA), St. Michael's Hospital (CA), Sunnybrook Health Science Centre (CA), University of Alberta (CA), University of Massachusetts Chan Medical School (US), University of Calgary (CA), University of Toronto (CA), Cornell University (US), Health Sciences Centre (CA), Institute for Clinical Evaluative Sciences (CA), UMass Memorial Medical Center (US), Weill Cornell Medicine (US)
Openalex Percentile: Top 14%
Sepsis Diagnosis and Treatment
1.35
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Variation in Maximal Doses of Vasopressors Used for Treatment of Shock in Intensive Care Units in Alberta Canada: A Retrospective Cohort Study — Ruxandra Pinto, Martin Chapman, et al. · Anesthesia & Analgesia (2025) | TGRS Research Map | TGRS