Explainable and externally validated machine learning for neurocognitive diagnosis via ECGs

These findings suggest that ECG holds promise as a non-invasive, explainable biomarker for selected neurocognitive disorders. This study demonstrates robust performance across cohorts and lays the groundwork for future clinical applications, including early detection and personalised monitoring.

Authors

Nils Strodthoff (ORCID: https://orcid.org/0000-0003-4447-0162)
Ebenezer Oloyede (ORCID: https://orcid.org/0000-0003-1352-4017)
Wilhelm Haverkamp (ORCID: https://orcid.org/0000-0002-6183-2519)
Juan Miguel Lopez Alcaraz (ORCID: https://orcid.org/0009-0008-3056-3521)
David Taylor

Institutions

Carl von Ossietzky Universität Oldenburg (DE)
King's College London (GB)
University of Oxford (GB)
Maudsley Hospital (GB)
Deutsches Herzzentrum München (DE)
Berlin Heart (Germany) (DE)

Publication Details

Journal: General Psychiatry
Published: 2025-10-01
DOI: https://doi.org/10.1136/gpsych-2025-102107
Primary Topic: ECG Monitoring and Analysis
Type: article
Field-Weighted Citation Impact: 0.00

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article

Explainable and externally validated machine learning for neurocognitive diagnosis via ECGs

Nils Strodthoff, Ebenezer Oloyede, Wilhelm Haverkamp, Juan Miguel Lopez Alcaraz et al.

Oct 1, 2025

General Psychiatry

ECG Monitoring and Analysis

article

Explainable and externally validated machine learning for neurocognitive diagnosis via ECGs

Nils Strodthoff, Ebenezer Oloyede, Wilhelm Haverkamp, Juan Miguel Lopez Alcaraz, David Taylor

October 1, 2025article en

Abstract

These findings suggest that ECG holds promise as a non-invasive, explainable biomarker for selected neurocognitive disorders. This study demonstrates robust performance across cohorts and lays the groundwork for future clinical applications, including early detection and personalised monitoring.

General PsychiatryVol. 38(5)

Carl von Ossietzky Universität Oldenburg (DE), King's College London (GB), University of Oxford (GB), Maudsley Hospital (GB), Deutsches Herzzentrum München (DE), Berlin Heart (Germany) (DE)

Openalex Percentile: Top 53%

ECG Monitoring and Analysis

DOI Open Access PDF OpenAlex

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Explainable and externally validated machine learning for neurocognitive diagnosis via ECGs — Nils Strodthoff, Ebenezer Oloyede, et al. · General Psychiatry (2025) | TGRS Research Map | TGRS