Integrated Expression Analysis May Support Serine/Threonine Kinases as Common Hub Genes in Breast Cancer.
Survival analysis showed that tumors with higher expression levels of hub genes were associated with significantly shorter overall survival times among breast cancer patients. This finding suggests that these hub genes are highly relevant to BC pathophysiology and could be considered targets for monitoring.
Authors
- Hamed Shahriarpour
- Ali Bigdeli (ORCID: https://orcid.org/0000-0001-8533-7320)
- Mostafa Ghaderi‐Zefrehei (ORCID: https://orcid.org/0000-0002-9710-883X)
- Effat Nasre Esfahani
- Mohammad Soleiman Ekhtiyari
- Maryam Yousefi (ORCID: https://orcid.org/0000-0002-1943-3733)
- Zahra Mogharari
- Bluma J Leschm
Institutions
- Tarbiat Modares University (IR)
- Islamic Azad University, Science and Research Branch (IR)
- Yasouj University (IR)
- University of Tabriz (IR)
Publication Details
- Journal
- PubMed
- Published
- 2025-10-01
- DOI
- https://doi.org/10.30476/ijms.2025.104386.3798
- Primary Topic
- Bioinformatics and Genomic Networks
- Type
- article
- Field-Weighted Citation Impact
- 0.00