Subcutaneous Chromoblastomycosis Caused by Rhinocladiella Species in Rhode Island.

Chromoblastomycosis (CBM) is a subcutaneous fungal infection caused by one of several dematiaceae molds with melanotic pigmentation in the cell walls. CBM is characterized by various clinical and dermatological features, leading to common misdiagnosis as several other infectious and noninfectious diseases. Histopathologically, in addition to the pathognomonic muriform cells or "copper pennies," the causative agents of subcutaneous and systemic mycosis lead to a granulomatous reaction due to the influx of mononuclear phagocytic cells and a suppurative infiltrate of neutrophils. Treatment of CBM can be challenging as no standard treatment has been established. This case highlights a rare presentation of subcutaneous chromoblastomycosis caused by Rhinocladiella species in the United States with satisfactory management. It emphasizes the role of occupational and exposure history, keeping a high index of suspicion in cases of verrucous nodules or plaques with new satellite lesions on extremities, and recognizing this entity's distinct dermatopathology characteristics.

Authors

Institutions

Publication Details

Journal
PubMed
Published
2025-11-03
Primary Topic
Fungal Infections and Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Subcutaneous Chromoblastomycosis Caused by Rhinocladiella Species in Rhode Island.

Bianca Biglione, M. A. Bharier, Andrew R. Blundell, Pavane Gorrepati et al.
PubMed
Fungal Infections and Studies
article

Subcutaneous Chromoblastomycosis Caused by Rhinocladiella Species in Rhode Island.

Bianca Biglione, M. A. Bharier, Andrew R. Blundell, Pavane Gorrepati, Jaclyn B. Anderson, Leslie Robinson-Bostom
article en

Abstract

Chromoblastomycosis (CBM) is a subcutaneous fungal infection caused by one of several dematiaceae molds with melanotic pigmentation in the cell walls. CBM is characterized by various clinical and dermatological features, leading to common misdiagnosis as several other infectious and noninfectious diseases. Histopathologically, in addition to the pathognomonic muriform cells or "copper pennies," the causative agents of subcutaneous and systemic mycosis lead to a granulomatous reaction due to the influx of mononuclear phagocytic cells and a suppurative infiltrate of neutrophils. Treatment of CBM can be challenging as no standard treatment has been established. This case highlights a rare presentation of subcutaneous chromoblastomycosis caused by Rhinocladiella species in the United States with satisfactory management. It emphasizes the role of occupational and exposure history, keeping a high index of suspicion in cases of verrucous nodules or plaques with new satellite lesions on extremities, and recognizing this entity's distinct dermatopathology characteristics.

PubMedVol. 108(11)
Brown University (US)
Openalex Percentile: Top 58%
Fungal Infections and Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.