Progress in the study of drug resistance mechanism of <i>Bacillus cereus</i>
Bacillus cereus is a common foodborne pathogen closely related to various foodborne diseases. The diarrhoea-type enterotoxins and vomiting-type enterotoxins it produces can lead to local or systemic infections. In recent years, resistance in B. cereus has been increasing, and multidrug-resistant bacteria have emerged. Therefore, understanding the drug resistance mechanism of B. cereus has become a matter of considerable concern in scientific research. In addition, this review explores the main resistance mechanisms of B. cereus to antibacterial drugs and discusses the detection and control strategies for the drug resistance of this bacterium. In addition, the purpose of this article is to deeply explore the drug resistance mechanism of B. cereus, with the aim of providing scientific basis and practical guidance for rational clinical drug use. Meanwhile, this article also provides innovative ideas for exploring new research approaches and screening safe and efficient antibacterial candidate drugs, with the aim of providing practical assistance for improving the current clinical cure rate.
Authors
- Xueli Wang (ORCID: https://orcid.org/0009-0001-0033-636X)
- Zhilin Liu (ORCID: https://orcid.org/0000-0003-4087-4901)
- Huisheng Xiong
- Jiayu Cui (ORCID: https://orcid.org/0009-0000-0794-1098)
- Song Han (ORCID: https://orcid.org/0000-0002-2914-3449)
- Yuhang Zhang (ORCID: https://orcid.org/0000-0001-6404-9952)
- Xin Zhang (ORCID: https://orcid.org/0000-0002-5795-9197)
- Dawei Wang (ORCID: https://orcid.org/0000-0001-7547-0689)
- Zelin Jia
Institutions
- Inner Mongolia University for Nationalities (CN)
- Tongliao Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-10-11
- DOI
- https://doi.org/10.1093/jac/dkaf399
- Citations
- 1
- Primary Topic
- Bacillus and Francisella bacterial research
- Type
- article
- Field-Weighted Citation Impact
- 0.81