Identification of Novel Modifier Genes Associated With Pain in Cystic Fibrosis: An In Silico Gene Discovery
This in silico analysis highlights potential genes and biochemical pathways implicated in pain pathways that could significantly impact pain perception in people living with CF and their response to prescribed therapies. Further functional analyses are needed to include CF participants and provide a physiological relevance on how genetic polymorphisms of identified GMs may impact their pain phenotype or profile.
Authors
- Anastasia Ward (ORCID: https://orcid.org/0000-0002-6597-934X)
- Chee Y. Ooi (ORCID: https://orcid.org/0000-0001-7111-0926)
- Ramil Mauleon (ORCID: https://orcid.org/0000-0001-8512-144X)
- Nedeljka Rosić (ORCID: https://orcid.org/0000-0002-2598-7046)
Institutions
- International Rice Research Institute (PH)
- UNSW Sydney (AU)
- Sydney Children's Hospital (AU)
- Southern Cross University (AU)
Publication Details
- Journal
- Human Mutation
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1155/humu/7570437
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Australian Government
- Southern Cross University
- Medical Research Council
- National Health and Medical Research Council