Significance of Serum Neuron‐Specific Enolase in Patients With Sepsis and Its Association With Inflammatory Biomarkers
Elevated NSE levels were observed in non-surviving patients with sepsis, and NSE levels on day 3 were significantly correlated with the other inflammation-related biomarkers. These findings suggest that the progression of brain damage due to sepsis may be associated with inflammation, highlighting a potential target for future therapeutic strategies.
Authors
- Umefumi Iguchi (ORCID: https://orcid.org/0000-0002-3363-4734)
- Toru Hosokawa (ORCID: https://orcid.org/0000-0002-0969-6054)
- Nami Sawada
- Atsushi Sakurai
- Kosaku Kinoshita (ORCID: https://orcid.org/0000-0002-9451-9027)
- Junko Yamaguchi (ORCID: https://orcid.org/0000-0002-6131-0665)
- Yasuyoshi Kai
- Shingo Ihara (ORCID: https://orcid.org/0000-0002-2963-415X)
- Katsuhiro Nakagawa
- Tsukasa Kuwana (ORCID: https://orcid.org/0000-0002-1798-0063)
Institutions
- Nihon University (JP)
- Nihon University Itabashi Hospital (JP)
Publication Details
- Journal
- Acute Medicine & Surgery
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/ams2.70094
- Primary Topic
- S100 Proteins and Annexins
- Type
- article
- Field-Weighted Citation Impact
- 0.00