Tunable stereoselectivity in a wireless electrochemical microreactor using natural chiral ionic liquids
A single drop of a natural chiral ionic liquid (NCIL) serves as a wireless electrochemical microreactor for enantioselective synthesis. This system yields high selectivity (>90% ee) and demonstrates dynamic stereocontrol, where the enantiomeric excess is directly modulated by the external electric field. This catalyst-free strategy introduces a new paradigm for sustainable, tunable asymmetric reactions.
Authors
- Andrea Mezzetta (ORCID: https://orcid.org/0000-0002-4540-9948)
- Sara Grecchi (ORCID: https://orcid.org/0000-0003-3868-8907)
- Lorenzo Guazzelli (ORCID: https://orcid.org/0000-0003-4655-2946)
- Serena Arnaboldi (ORCID: https://orcid.org/0000-0002-1981-4659)
Institutions
- University of Pisa (IT)
- University of Milan (IT)
Publication Details
- Journal
- Green Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5gc04756k
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Horizon 2020 Framework Programme
- H2020 European Research Council