Treatment intensity-dependent association between the number of oral hypoglycemic agents and insulin use and lung cancer risk in patients with type 2 diabetes
A higher number of OHAs was associated with an increased risk of lung cancer in a treatment-intensity-dependent association, and insulin users exhibited the greatest risk in type 2 diabetes. Lung cancer risk was augmented if individuals were aged <65 years, males, current smokers, or heavy drinkers.
Authors
- Kyu Na Lee
- Sei Won Lee (ORCID: https://orcid.org/0000-0003-4814-6730)
- Dong Wook Shin (ORCID: https://orcid.org/0000-0001-8128-8920)
- Kyungdo Han (ORCID: https://orcid.org/0000-0002-9622-0643)
- Chiwook Chung (ORCID: https://orcid.org/0000-0002-5643-6095)
Institutions
- Ulsan College (KR)
- Soongsil University (KR)
- Samsung (South Korea) (KR)
- Asan Medical Center (KR)
- Samsung Medical Center (KR)
- University of Ulsan (KR)
- Hallym University Dongtan Sacred Heart Hospital (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Translational Lung Cancer Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/tlcr-2025-680
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00