Feasibility of next-generation sequencing using bronchoscopic specimens in potentially resectable non-small cell lung cancer

The overall rate of successful NGS analysis using bronchoscopic specimens were lower in potentially resectable NSCLC cases, especially in lung lesions. To improve NGS feasibility, it is important to adequately harvest lung lesions and prioritize targeting endobronchial or peri-tracheal/bronchial lesions.

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Publication Details

Journal
Translational Lung Cancer Research
Published
2025-10-01
DOI
https://doi.org/10.21037/tlcr-2025-605
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Feasibility of next-generation sequencing using bronchoscopic specimens in potentially resectable non-small cell lung cancer

Kaito Yano, Yuji Matsumoto, Keigo Uchimura, Tatsuya Imabayashi et al.
Translational Lung Cancer Research
Lung Cancer Diagnosis and Treatment
article

Feasibility of next-generation sequencing using bronchoscopic specimens in potentially resectable non-small cell lung cancer

Kaito Yano, Yuji Matsumoto, Keigo Uchimura, Tatsuya Imabayashi, Takaaki Tsuchida, Hideaki Furuse, Keisuke Asakura
article en

Abstract

The overall rate of successful NGS analysis using bronchoscopic specimens were lower in potentially resectable NSCLC cases, especially in lung lesions. To improve NGS feasibility, it is important to adequately harvest lung lesions and prioritize targeting endobronchial or peri-tracheal/bronchial lesions.

Translational Lung Cancer ResearchVol. 14(10)
Keio University (JP), National Cancer Center Hospital East (JP)
Openalex Percentile: Top 55%
Lung Cancer Diagnosis and Treatment
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Feasibility of next-generation sequencing using bronchoscopic specimens in potentially resectable non-small cell lung cancer — Kaito Yano, Yuji Matsumoto, et al. · Translational Lung Cancer Research (2025) | TGRS Research Map | TGRS