Investigation of non-completion factors for durvalumab maintenance therapy in locally advanced non-small cell lung cancer
Low-dose carboplatin CCRT is associated with lower durvalumab completion rates and worse outcomes, particularly in older patients. Alternative CCRT regimens may warrant consideration, particularly for older patients who are less likely to complete durvalumab maintenance.
Authors
- Akira Toyama (ORCID: https://orcid.org/0000-0002-4802-2984)
- Satoshi Watanabe (ORCID: https://orcid.org/0000-0003-0041-6981)
- Toshiaki Kikuchi (ORCID: https://orcid.org/0000-0001-7428-1245)
- Masaaki Kotake (ORCID: https://orcid.org/0009-0008-5433-4854)
- Yuki Sakai (ORCID: https://orcid.org/0009-0007-4631-3968)
Institutions
- Niigata University Medical and Dental Hospital (JP)
- Niigata University (JP)
Publication Details
- Journal
- Translational Lung Cancer Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/tlcr-2025-739
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.00