Overall survival and progression-free survival of patients with non-small cell lung cancer and either limited or extensive synchronous metastatic spread in Germany—a population-based cancer registry cohort study

Stratification of synchronous metastatic NSCLC by extent of metastatic spread, including further differentiation within M1c, revealed clear differences in OS and PFS. These findings suggest that the number of organ systems involved may be a clinically relevant parameter and support further evaluation of subclassification approaches in population-based cohorts.