Alkaline Extracts in Ayurveda: A Comprehensive Review on Paneeya Kshara Kalpana

Background: Paneeya Kshara Kalpana is a dosage form described extensively in compendia but has not remained popular in practice.There is a need to explore Paneeya Kshara and provide scientific evidence to dispel misconceptions regarding its use.Paneeya Kshara therapy minimizes complications, reduces disease recurrence, and decreases the risk of postoperative infections due to its alkalinity.Its use will be cost-effective than many other dosage forms.According to Acharya Sushruta, Kshara holds great importance in both surgical measures and para-surgical measures.Hence, the present study was conducted to explore the significance of Paneeya Kshara Kalpana.Aim and objectives: To explore the pharmaceutics and therapeutics of Paneeya Kshara Kalpana.Materials and methods: The study was conducted through an extensive review of classical Ayurvedic compendia, including texts on Rasa Shastra and Bhaishajya Kalpana.In addition, relevant research articles, digital libraries, e-resources, and magazines were thoroughly explored to gather contemporary insights and updates related to Paneeya Kshara Kalpana.Both traditional and modern sources were critically analyzed to compile comprehensive information on its formulation, preparation methods, therapeutic applications, and pharmaceutical relevance of Paneeya Kshara.Observations and results: A few pre-clinical and clinical trials show the potent efficacy of the drug.Conclusion: There is a pressing need for further scientific research to evaluate the efficacy and safety of Paneeya Kshara.Comprehensive studies are essential to establish its therapeutic potential, standardize dosage, and ensure its safe application in clinical practice.