Reduced Pain Responses With a Digital Automatic Syringe: Behavioral and Molecular Evidence in a Rodent Formalin Model
The I-ject™ automatic syringe markedly reduced both behavioral signs of pain and molecular markers of nociceptive activation in this rodent formalin pain model. These findings support the potential of this digital automatic injection system as a safer and more consistent alternative to conventional manual syringes in both preclinical research and clinical settings.
Authors
- Chan Yeong Heo (ORCID: https://orcid.org/0000-0001-9003-7365)
- Changhai Jin (ORCID: https://orcid.org/0000-0003-2839-813X)
- Pham Ngoc Chien (ORCID: https://orcid.org/0000-0003-1419-3766)
- Y. Jin
- Y Lee
- YEOM HYUN-CHEOL
Institutions
- Seoul National University (KR)
- Seoul National University Bundang Hospital (KR)
- National University College (PR)
- EuBiologics (South Korea) (KR)
Publication Details
- Journal
- In Vivo
- Published
- 2025-10-29
- DOI
- https://doi.org/10.21873/invivo.14129
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Korea Health Industry Development Institute
- Ministry of Science and ICT, South Korea