Investigation of MicroRNA-30d-5p Expression and SOCS3 Levels in Non-small Cell Lung Cancer
Increased SOCS3 and decreased miR-30d-5p expression were observed in patients with NSCLC, indicating their involvement in tumor progression and immune disruption. The inverse correlation between these biomarkers suggests a regulatory interaction that may influence the JAK/STAT signaling pathway. These findings highlight the diagnostic and therapeutic potential of targeting the miR-30d-5p/SOCS3 axis in NSCLC.
Authors
- Selvi Duman Bakırezer
- Seda Güleç Yılmaz (ORCID: https://orcid.org/0000-0002-8119-2862)
- Seha Akduman (ORCID: https://orcid.org/0000-0002-9606-6834)
- Huseyin Kilili (ORCID: https://orcid.org/0000-0002-4160-5888)
- Sibel Arınç (ORCID: https://orcid.org/0000-0002-2443-2639)
- Müge Kopuz Álvarez Noval (ORCID: https://orcid.org/0000-0001-6072-4607)
Institutions
- Yeditepe University (TR)
- Chest Diseases Hospital (KW)
- Sağlık Bilimleri Üniversitesi (TR)
- Yeditepe University Hospital (TR)
Publication Details
- Journal
- In Vivo
- Published
- 2025-10-29
- DOI
- https://doi.org/10.21873/invivo.14106
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00