Pressure-induced phase behaviour and compressibility of the racemic and chiral solid forms, ofloxacin and levofloxacin

High-pressure crystallography of three related fluoroquinolone solid forms reveals distinct phase behaviour under compression providing understanding of API stability under processing conditions.

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Publication Details

Journal
CrystEngComm
Published
2025-01-01
DOI
https://doi.org/10.1039/d5ce00855g
Primary Topic
Crystallography and molecular interactions
Type
article
Field-Weighted Citation Impact
0.00

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article

Pressure-induced phase behaviour and compressibility of the racemic and chiral solid forms, ofloxacin and levofloxacin

Martin R. Ward, H. Michael, Mark R. Warren, Davide Comboni et al.
CrystEngComm
Crystallography and molecular interactions
article

Pressure-induced phase behaviour and compressibility of the racemic and chiral solid forms, ofloxacin and levofloxacin

Martin R. Ward, H. Michael, Mark R. Warren, Davide Comboni, Andrew G. P. Maloney, Rebecca Scatena, Iain D. H. Oswald, Julia Gasol-Cardona
article en

Abstract

High-pressure crystallography of three related fluoroquinolone solid forms reveals distinct phase behaviour under compression providing understanding of API stability under processing conditions.

CrystEngCommVol. 27(47)
University of Strathclyde (GB), European Synchrotron Radiation Facility (FR), Diamond Light Source (GB), Cambridge Crystallographic Data Centre (GB)
Engineering and Physical Sciences Research Council
Openalex Percentile: Top 71%
Crystallography and molecular interactions
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