Perioperative anti-α4β7 Integrin Blockade Alters Wound Cell Infiltrate but Not the Functional Outcome of Ileocecal Anastomoses in Mice With Crohn’s-like Ileitis
Crohn's-like ileitis mice were at higher risk for abscess formation. Anti-α4β7 integrin treatment resulted in cellular changes that did not impair functional anastomotic healing.
Authors
- André Fischer (ORCID: https://orcid.org/0000-0002-6386-2324)
- Georg Lamprecht (ORCID: https://orcid.org/0000-0003-0997-3135)
- Marcel Kordt (ORCID: https://orcid.org/0000-0002-5826-1217)
- Clemens Schafmayer (ORCID: https://orcid.org/0000-0002-4096-5005)
- Peggy Berlin (ORCID: https://orcid.org/0000-0001-8354-6970)
- Johannes Reiner
- Maria Witte (ORCID: https://orcid.org/0000-0001-6746-7260)
- Wendy Bergmann‐Ewert (ORCID: https://orcid.org/0000-0001-7221-3900)
Institutions
- University of Rostock (DE)
Publication Details
- Journal
- Inflammatory Bowel Diseases
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1093/ibd/izaf223
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00