Impact of Discontinuation of Contact Precautions on Healthcare-associated ESBL-producing <i>Escherichia coli</i> in a Large Tertiary Care Hospital: An Interrupted Time-series Analysis
At Geneva University Hospitals, contact precautions for ESBL-producing Escherichia coli were discontinued in 2019. Among 2,336 hospital-associated cases from 2016 to 2024, incidence was 3.1 per 10,000 patient days at baseline and showed no significant increase after discontinuation (slope change -0.04, p=0.14). Results were consistent when limited to clinical isolates.
Authors
- Jonathan Sobel (ORCID: https://orcid.org/0000-0002-5111-4070)
- Rebecca Grant (ORCID: https://orcid.org/0000-0001-8412-8113)
- S Musumeci (ORCID: https://orcid.org/0000-0002-2422-1217)
- Niccolò Buetti (ORCID: https://orcid.org/0000-0002-8096-1834)
- Abdessalam Cherkaoui (ORCID: https://orcid.org/0000-0002-1801-5935)
- Stéphan Harbarth
Institutions
- University Hospital of Geneva (CH)
- Geneva College (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1093/cid/ciaf594
- Primary Topic
- Infection Control in Healthcare
- Type
- article
- Field-Weighted Citation Impact
- 0.00