PRP-loaded hydrogel for rotator cuff repair by promoting osteogenic differentiation and tendon regeneration
The PRP-CMCS-TA composite hydrogel exhibits good biocompatibility and effectively repairs the tendon-bone interface by promoting osteogenic differentiation and tendon regeneration. This study provides new insights into the application of bioactive materials for rotator cuff injuries and offers a promising strategy for improving the outcomes of rotator cuff repair. Further research and clinical trials are needed to translate these findings into practical applications and to establish the hydrogel as a standard treatment option for rotator cuff injuries.
Authors
- Y. Ye
- Jiaqin Yuan
- Z. D. Liu (ORCID: https://orcid.org/0000-0001-5862-6063)
- Zhixiang Zhuang (ORCID: https://orcid.org/0000-0003-3717-615X)
- R Zhang
- C. Luo
- Guo‐Qing Zhu (ORCID: https://orcid.org/0000-0002-3132-9592)
- Zhaoliang Zheng (ORCID: https://orcid.org/0000-0001-6741-6148)
- Qingchu Li (ORCID: https://orcid.org/0000-0003-4351-5824)
- Xizhao Huang (ORCID: https://orcid.org/0009-0004-3097-652X)
Institutions
- Third Affiliated Hospital of Southern Medical University (CN)
- Guangdong Province Women and Children Hospital (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-10-30
- DOI
- https://doi.org/10.3389/fbioe.2025.1655809
- Primary Topic
- Shoulder Injury and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00