Selective Hippocampal Subfield Atrophy Mediates Cognitive Decline in Cushing's Disease
CD patients exhibit distinct patterns of hippocampal atrophy affecting specific subfields, with changes correlating to hormone levels and cognitive symptoms. These structural alterations may serve as potential biomarkers for CD and provide insight into the mechanisms underlying cognitive dysfunction in hypercortisolism.
Authors
- Yanyang Zhang (ORCID: https://orcid.org/0000-0003-2162-7358)
- Kunyu He
- Zhebin Feng
- Xinyuan Yan (ORCID: https://orcid.org/0000-0003-3373-330X)
- Hailong Liu (ORCID: https://orcid.org/0000-0002-6181-2577)
- Tao Zhou (ORCID: https://orcid.org/0009-0006-8491-8477)
- Xinguang Yu
- Rong Lu
- Zhiguo Ma (ORCID: https://orcid.org/0000-0002-4752-8246)
- Xiaoteng Yu
Institutions
- Peking University (CN)
- Chinese PLA General Hospital (CN)
- Beijing Tian Tan Hospital (CN)
- Ningxia Hui Autonomous Region Peoples Hospital (CN)
- Ningxia Medical University (CN)
- Peking University First Hospital (CN)
- University of Minnesota Medical Center (US)
- First Hospital of Xi'an (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1002/brb3.71030
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- General Hospital of People’s Liberation Army
- National Science and Technology Major Project