Dissecting Causal Relationships Between Gut Microbiota Imbalance, Inflammatory Cytokines, and Structural Connectivity in the Brain: A Mendelian Randomization Study
This research establishes potential causal links between gut microbiota and brain structural connectivity, bridging a crucial gap in the microbiota-gut-brain axis research. These findings enhance our understanding of the axis and suggest new therapeutic targets for neurological disorders.
Authors
- Aamir Fahira (ORCID: https://orcid.org/0000-0001-5501-6884)
- Ying Wen (ORCID: https://orcid.org/0000-0003-1692-1384)
- Qing Zhong (ORCID: https://orcid.org/0000-0002-8214-9129)
- Zunnan Huang (ORCID: https://orcid.org/0000-0002-5821-703X)
- Jiahao Yang (ORCID: https://orcid.org/0009-0000-7496-6455)
- Qiao‐Nan Guo (ORCID: https://orcid.org/0000-0002-5074-0838)
- Kai Zhuang (ORCID: https://orcid.org/0000-0003-1724-6210)
- Dongli Yang (ORCID: https://orcid.org/0000-0001-5026-3149)
- Zhonglin Tang (ORCID: https://orcid.org/0000-0002-4538-4349)
Institutions
- Guangdong Medical College (CN)
- Guangdong Pharmaceutical University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Songshan Lake Materials Laboratory (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1002/brb3.70980
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81