Differentiation of α2–3‐ and α2–6‐Linked Sialic Acid Linkages Using Esterification/Amidation Reactions and Tandem Mass Spectrometry
The proposed tandem mass spectrometry enables accurate differentiation of α2 → 3 and α2 → 6 sialic acid linkages, even when both of them undergo amidation or esterification.
Authors
- Wei‐Chien Weng (ORCID: https://orcid.org/0000-0001-9838-5356)
- Chi‐Kung Ni (ORCID: https://orcid.org/0000-0001-6503-8905)
- Chin‐Yu Liang
- Ching‐Ching Yu (ORCID: https://orcid.org/0000-0003-2103-6419)
- Hsin‐Kai Tseng (ORCID: https://orcid.org/0000-0002-8579-6196)
- Chun‐Cheng Lin (ORCID: https://orcid.org/0000-0002-2323-0920)
- Hsien‐Wei Tseng
Institutions
- National Chung Cheng University (TW)
- National Tsing Hua University (TW)
- Institute of Atomic and Molecular Sciences, Academia Sinica (TW)
- Institute of Molecular Biology, Academia Sinica (TW)
Publication Details
- Journal
- Rapid Communications in Mass Spectrometry
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1002/rcm.10165
- Primary Topic
- Mass Spectrometry Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00