Efficacy and influencing factors analysis of SGLT2 inhibitors in treating heart failure following acute myocardial infarction
SGLT2 inhibitors were associated with enhanced cardiac function and reduce cardiac stress markers in HF patients post-AMI, suggesting their potential as an adjunctive therapy. Lower baseline LVEF and higher NT-proBNP levels may predict better response, suggesting their utility in personalized treatment strategies. This was a retrospective single-center study, and further prospective trials are needed to confirm these findings.
Authors
- Haiping Du (ORCID: https://orcid.org/0009-0000-7073-9079)
- Hui Xu (ORCID: https://orcid.org/0000-0002-7072-1706)
- Jinwei Bao
Institutions
- Yantaishan Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-10-30
- DOI
- https://doi.org/10.3389/fphar.2025.1693420
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00