Comprehensive analysis of risk factors and metabolic profiling in preclinical atherosclerosis: a cross-sectional study
The incidence of PCA is influenced by smoking, unhealthy diet habits, hypertension, and diabetes. PCA patients frequently exhibit abnormalities in lipid metabolism, glucose metabolism, and purine metabolism. Metabolomic studies indicate that the metabolic differences in PCA primarily involve lipid metabolism, energy metabolism, and amino acid metabolism.
Authors
- Fengrong Wang
- Tiehong Liu
- Li Liu (ORCID: https://orcid.org/0000-0003-1239-3705)
- Tianjiao Zhang (ORCID: https://orcid.org/0000-0001-8355-9253)
- Guo-ling Hu
- Linlin Dong
- Lijie Jiang (ORCID: https://orcid.org/0000-0003-4553-982X)
Institutions
- Affiliated Hospital of Liaoning University of Traditional Chinese Medicine (CN)
- Affiliated Zhongshan Hospital of Dalian University (CN)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-10-30
- DOI
- https://doi.org/10.3389/fphys.2025.1677194
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00