Portfolio analysis of single-cell RNA-sequencing and transcriptomic data unravels immune cells and telomere-related biomarkers in sepsis

This study identified 4 biomarkers, namely <i>MYO10</i>, <i>SULT1B1</i>, <i>MKI67</i>, and <i>CREB5</i> and explored the pathogenesis of sepsis, providing new insights for potential treatment strategies by integrating transcriptomic data and single-cell analysis.

Authors

Xiyi Huang
Chun Wang (ORCID: https://orcid.org/0000-0002-8233-6055)
Dan Chen (ORCID: https://orcid.org/0000-0001-8118-4443)
Cheng Zheng (ORCID: https://orcid.org/0000-0003-1402-9827)
Yunhao Liu (ORCID: https://orcid.org/0000-0002-0279-1307)

Institutions

Wuhan University of Technology (CN)
Shantou University (CN)
Shantou University Medical College (CN)
Wuhan University of Science and Technology (CN)
Huazhong University of Science and Technology (CN)

Publication Details

Journal: Frontiers in Immunology
Published: 2025-10-30
DOI: https://doi.org/10.3389/fimmu.2025.1638156
Primary Topic: Single-cell and spatial transcriptomics
Type: article
Field-Weighted Citation Impact: 0.00

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

Portfolio analysis of single-cell RNA-sequencing and transcriptomic data unravels immune cells and telomere-related biomarkers in sepsis

Xiyi Huang, Chun Wang, Dan Chen, Cheng Zheng et al.

Oct 30, 2025

Frontiers in Immunology

Single-cell and spatial transcriptomics

article

Portfolio analysis of single-cell RNA-sequencing and transcriptomic data unravels immune cells and telomere-related biomarkers in sepsis

Xiyi Huang, Chun Wang, Dan Chen, Cheng Zheng, Yunhao Liu

October 30, 2025article en

Abstract

This study identified 4 biomarkers, namely <i>MYO10</i>, <i>SULT1B1</i>, <i>MKI67</i>, and <i>CREB5</i> and explored the pathogenesis of sepsis, providing new insights for potential treatment strategies by integrating transcriptomic data and single-cell analysis.

Frontiers in ImmunologyVol. 16

Wuhan University of Technology (CN), Shantou University (CN), Shantou University Medical College (CN), Wuhan University of Science and Technology (CN), Huazhong University of Science and Technology (CN)

Openalex Percentile: Top 72%

Single-cell and spatial transcriptomics

DOI Open Access PDF OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Portfolio analysis of single-cell RNA-sequencing and transcriptomic data unravels immune cells and telomere-related biomarkers in sepsis — Xiyi Huang, Chun Wang, et al. · Frontiers in Immunology (2025) | TGRS Research Map | TGRS