Exploring common circulating diagnostic biomarkers for sleep disorders and stroke based on machine learning

This study provides insights into the common molecular mechanisms of SD and stroke, highlighting the potential of ARL2 as a diagnostic marker and therapeutic target. Unlike previous studies, we used circulating markers rather than tissue markers, improving the clinical translation in terms of non-invasive, rapid identification of patients at risk for sleep disorders. We need to further investigate the functional role of these genes and their potential in developing targeted therapies for SD and stroke patients.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-10-30
DOI
https://doi.org/10.3389/fneur.2025.1599135
Primary Topic
Sleep and Wakefulness Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring common circulating diagnostic biomarkers for sleep disorders and stroke based on machine learning

Xiangzhe Liu, Hanlin Yu, Zhen Wang, Yongwei Zhang et al.
Frontiers in Neurology
Sleep and Wakefulness Research
article

Exploring common circulating diagnostic biomarkers for sleep disorders and stroke based on machine learning

Xiangzhe Liu, Hanlin Yu, Zhen Wang, Yongwei Zhang, Shuya Cai
article en

Abstract

This study provides insights into the common molecular mechanisms of SD and stroke, highlighting the potential of ARL2 as a diagnostic marker and therapeutic target. Unlike previous studies, we used circulating markers rather than tissue markers, improving the clinical translation in terms of non-invasive, rapid identification of patients at risk for sleep disorders. We need to further investigate the functional role of these genes and their potential in developing targeted therapies for SD and stroke patients.

Frontiers in NeurologyVol. 16
Dalian Medical University (CN), Second Affiliated Hospital of Dalian Medical University (CN), First Affiliated Hospital of Dalian Medical University (CN), First Affiliated Hospital of Henan University (CN)
Openalex Percentile: Top 69%
Sleep and Wakefulness Research
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