Exploring common circulating diagnostic biomarkers for sleep disorders and stroke based on machine learning
This study provides insights into the common molecular mechanisms of SD and stroke, highlighting the potential of ARL2 as a diagnostic marker and therapeutic target. Unlike previous studies, we used circulating markers rather than tissue markers, improving the clinical translation in terms of non-invasive, rapid identification of patients at risk for sleep disorders. We need to further investigate the functional role of these genes and their potential in developing targeted therapies for SD and stroke patients.
Authors
- Xiangzhe Liu (ORCID: https://orcid.org/0000-0002-0479-7753)
- Hanlin Yu (ORCID: https://orcid.org/0009-0009-0675-6865)
- Zhen Wang (ORCID: https://orcid.org/0000-0003-4134-1779)
- Yongwei Zhang (ORCID: https://orcid.org/0000-0001-9958-3098)
- Shuya Cai
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-10-30
- DOI
- https://doi.org/10.3389/fneur.2025.1599135
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00