Exploring Desmin as a Potential Modifier in Duchenne Muscular Dystrophy–Associated Cardiomyopathy
Increased filamentous desmin appears to be protective in mdx mouse hearts and may modulate the severity of DMD cardiomyopathy. These findings support a modifier role for desmin and highlight this protein as a potential therapeutic target for DMD.
Authors
- Yeranuhi Hovhannisyan (ORCID: https://orcid.org/0000-0002-5178-9457)
- Brice‐Emmanuel Guennec
- Caroline Cieniewski‐Bernard (ORCID: https://orcid.org/0000-0003-1449-0357)
- Stéphane Blot (ORCID: https://orcid.org/0000-0002-8982-0317)
- Inès Barthélémy (ORCID: https://orcid.org/0000-0002-4747-5893)
- Ekaterini Kordeli (ORCID: https://orcid.org/0000-0002-5115-2202)
- Zhenlin Li (ORCID: https://orcid.org/0000-0002-3706-4505)
- Arnaud Ferry (ORCID: https://orcid.org/0000-0002-6050-4556)
- Nathalie Mougenot (ORCID: https://orcid.org/0000-0002-7707-234X)
- Medhi Hassani (ORCID: https://orcid.org/0000-0001-6498-1344)
- Onnik Agbulut (ORCID: https://orcid.org/0000-0003-1923-8871)
- Sanem Eryılmaz Polat (ORCID: https://orcid.org/0000-0003-2309-7952)
- Gaëlle Revet
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- École Nationale Vétérinaire d'Alfort (FR)
- Sorbonne Université (FR)
- Centre d'Économie de la Sorbonne (FR)
- Sorbonne Paris Cité (FR)
- Institut de Biologie Paris-Seine (FR)
- Unité de Glycobiologie Structurale et Fonctionnelle (FR)
- Centre de Recherche Saint-Antoine (FR)
- Institut Mondor de Recherche Biomédicale (FR)
- Centre de Recherche en Myologie
- UMS Phénotypage du petit animal (FR)
- Développement Adaptation et Vieillissement (FR)
Publication Details
- Journal
- Acta Physiologica
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1111/apha.70117
- Citations
- 1
- Primary Topic
- Skin and Cellular Biology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.15