Clinical efficacy of JAK inhibitors for RA patients with poor-prognosis factors: the ANSWER cohort study
JAKi treatment provided sustained disease control (especially in high-risk RA patients) and promoted GC reduction. Although TNFi remains a standard option, JAKi treatment may be preferable in patients with 4PPFs. Further research should evaluate JAKi treatment's long-term safety and efficacy.
Authors
- Koji Kinoshita (ORCID: https://orcid.org/0000-0003-1809-5143)
- Kohei Tsujimoto (ORCID: https://orcid.org/0000-0001-6958-2983)
- Chisato Ashida (ORCID: https://orcid.org/0000-0003-3137-0138)
- Sho Sendo (ORCID: https://orcid.org/0000-0002-7193-341X)
- Toshihiko Shiga (ORCID: https://orcid.org/0009-0008-3110-4976)
- Motomu Hashimoto (ORCID: https://orcid.org/0000-0002-9241-060X)
- Daisuke Tomita (ORCID: https://orcid.org/0000-0001-9762-5055)
- Yuji Nozaki (ORCID: https://orcid.org/0000-0003-2810-1519)
- Koichi Murata (ORCID: https://orcid.org/0000-0002-7896-3937)
- Tadashi Okano (ORCID: https://orcid.org/0000-0002-8849-9824)
- Tetsu Itami (ORCID: https://orcid.org/0009-0000-9991-4176)
- Hideyuki Shiba (ORCID: https://orcid.org/0000-0002-9785-4533)
- Akira Ōnishi (ORCID: https://orcid.org/0000-0002-3120-1273)
- Yonsu Son (ORCID: https://orcid.org/0000-0001-7244-7715)
- Yumi Morimoto
- Wataru Yamamoto (ORCID: https://orcid.org/0000-0002-0810-4221)
- Naofumi Yoshida (ORCID: https://orcid.org/0000-0002-7015-377X)
- Rika Fukuda
- H. Yamada (ORCID: https://orcid.org/0000-0002-8090-6755)
- Y Hiramatsu (ORCID: https://orcid.org/0000-0003-0944-7186)
- Kazuya Kishimoto
Institutions
- Kansai Medical University (JP)
- Kyoto University (JP)
- Kurashiki Central Hospital (JP)
- Kindai University Hospital (JP)
- Osaka Metropolitan University (JP)
- Kobe University (JP)
- Osaka University of Pharmaceutical Sciences (JP)
- Kindai University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1093/rheumatology/keaf552
- Primary Topic
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00