Investigation of production routes for various radioisotopes and their excitation function studies significant to PET technology

Excitation functions for the production route of light non-metallic radioisotopes 11C, 13N, 15O and 18F and metallic radioisotope 64Cu are evaluated using the statistical model code EMPIRE-3.2. The radioisotopes studied are commonly used in positron emission tomography and single-photon emission computed tomography technologies. The effect of pre-equilibrium emission, nuclear level densities and the optical model potential on the reaction cross-sections has been studied and validated through reported experimental values and an evaluated data library (TENDL). The results of the performed calculations with best-fit values as obtained from different pre-equilibrium emission models, level density models and the optical model potential parameters provide reliable values of the cross-section in a broad spectrum of energies, also including the region where no experimental data are available, thus exposing a possible production route in the required energy range.

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Journal
Journal of Taibah University for Science
Published
2025-10-29
DOI
https://doi.org/10.1080/16583655.2025.2572147
Primary Topic
Radiopharmaceutical Chemistry and Applications
Type
article
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article

Investigation of production routes for various radioisotopes and their excitation function studies significant to PET technology

Kailash Pandey, D. P. Singh, Kuldeep Kholiya, Milan Singh
Journal of Taibah University for Science
Radiopharmaceutical Chemistry and Applications
article

Investigation of production routes for various radioisotopes and their excitation function studies significant to PET technology

Kailash Pandey, D. P. Singh, Kuldeep Kholiya, Milan Singh
article en

Abstract

Excitation functions for the production route of light non-metallic radioisotopes 11C, 13N, 15O and 18F and metallic radioisotope 64Cu are evaluated using the statistical model code EMPIRE-3.2. The radioisotopes studied are commonly used in positron emission tomography and single-photon emission computed tomography technologies. The effect of pre-equilibrium emission, nuclear level densities and the optical model potential on the reaction cross-sections has been studied and validated through reported experimental values and an evaluated data library (TENDL). The results of the performed calculations with best-fit values as obtained from different pre-equilibrium emission models, level density models and the optical model potential parameters provide reliable values of the cross-section in a broad spectrum of energies, also including the region where no experimental data are available, thus exposing a possible production route in the required energy range.

Journal of Taibah University for ScienceVol. 19(1)
Kumaun University (IN), National Institute of Technology, Kumamoto College (JP), Universidad Politécnica de El Salvador (SV), University of Petroleum and Energy Studies (IN)
Openalex Percentile: Top 54%
Radiopharmaceutical Chemistry and Applications
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Investigation of production routes for various radioisotopes and their excitation function studies significant to PET technology — Kailash Pandey, D. P. Singh, et al. · Journal of Taibah University for Science (2025) | TGRS Research Map | TGRS