Decoding the air pollutant–psoriasis axis: A multi-layered systems toxicology investigation
Our integrative framework combining network toxicology and machine learning provides novel insights into the immunotoxic mechanisms linking air pollution and psoriasis, highlighting candidate biomarkers and supporting future environmental health interventions.
Authors
- Yashpal S. Kanwar (ORCID: https://orcid.org/0000-0003-1059-639X)
- Xiaorui Qiu
- Yantao Xu (ORCID: https://orcid.org/0000-0002-5575-8332)
- Fangzhi Chen (ORCID: https://orcid.org/0000-0002-3075-2225)
- Zixi Jiang (ORCID: https://orcid.org/0000-0002-1744-9782)
- Jiachen Liu (ORCID: https://orcid.org/0000-0002-0263-3704)
- Wenpeng Wang (ORCID: https://orcid.org/0000-0002-0775-6447)
Institutions
- Northwestern University (US)
- Central South University (CN)
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
- Second Xiangya Hospital of Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2025-10-30
- DOI
- https://doi.org/10.1016/j.ecoenv.2025.119297
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00