Recommendations for the diagnosis and treatment of spontaneous intracranial hypotension

Spontaneous intracranial hypotension (SIH) is a syndrome characterized by disabling orthostatic headache, resulting from a reduction in volume of cerebrospinal fluid (CSF) likely caused by a CSF leak. It mainly affects women at working age and is probably underdiagnosed. This protocol aims to present a proposal for a practical approach to the diagnosis and treatment of SIH. After a descriptive section of the clinical manifestations of SIH, we present a step-by-step model of action to confirm its diagnosis and treatment, considering different clinical scenarios. The aim is, therefore, to facilitate clinical decision-making through a systematized and individualized approach, aiming to best interest of the patient.

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Publication Details

Journal
La radiologia medica
Published
2025-10-30
DOI
https://doi.org/10.1007/s11547-025-02116-6
Primary Topic
Neurosurgical Procedures and Complications
Type
article
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article

Recommendations for the diagnosis and treatment of spontaneous intracranial hypotension

Luigi Cirillo, Francesco Causin, Alessandra Splendiani, Elisa Ciceri et al.
La radiologia medica
Neurosurgical Procedures and Complications
article

Recommendations for the diagnosis and treatment of spontaneous intracranial hypotension

Luigi Cirillo, Francesco Causin, Alessandra Splendiani, Elisa Ciceri, Ferdinando Caranci, Mauro Bergui
article en

Abstract

Spontaneous intracranial hypotension (SIH) is a syndrome characterized by disabling orthostatic headache, resulting from a reduction in volume of cerebrospinal fluid (CSF) likely caused by a CSF leak. It mainly affects women at working age and is probably underdiagnosed. This protocol aims to present a proposal for a practical approach to the diagnosis and treatment of SIH. After a descriptive section of the clinical manifestations of SIH, we present a step-by-step model of action to confirm its diagnosis and treatment, considering different clinical scenarios. The aim is, therefore, to facilitate clinical decision-making through a systematized and individualized approach, aiming to best interest of the patient.

La radiologia medicaVol. 131(2)
University of Padua (IT), University of L'Aquila (IT), Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT), Ospedale Antonio Cardarelli (IT), Fatebenefratelli Hospital (IT), Department of Physiological Sciences (RU), Istituto delle Scienze Neurologiche di Bologna (IT), University of Campania "Luigi Vanvitelli" (IT), Azienda Ospedale - Università Padova (IT), Fondazione IRCCS Istituto Neurologico Carlo Besta (IT), University of Bologna (IT)
Openalex Percentile: Top 55%
Neurosurgical Procedures and Complications
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