A case series of adenomyoepithelioma of the breast with a case of malignant adenomyoepithelioma misinterpreted as polymorphous adenocarcinoma
This case series underscores the diagnostic challenges and importance of accurate differentiation between AME, MAME, and PmA, as misdiagnosis can significantly impact treatment and prognosis and highlighting the importance of IHC and molecular profiling. Given the potential for recurrence and metastasis, complete excision with negative margins remains the mainstay of treatment. This series contributes to the limited literature on these rare tumors, emphasizing the critical role of meticulous pathological evaluation and multidisciplinary approaches to improve patient outcomes.
Authors
- Eli Avisar (ORCID: https://orcid.org/0000-0003-0771-464X)
- Siarhei Melnikau (ORCID: https://orcid.org/0000-0003-2755-556X)
- Christina Layton
- Carmen Gómez
- Maria Paz De la Torre (ORCID: https://orcid.org/0009-0004-9550-8129)
Institutions
- University of Miami (US)
- Florida Atlantic University (US)
Publication Details
- Journal
- AME Case Reports
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/acr-24-178
- Primary Topic
- Breast Lesions and Carcinomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00