A Glycerophospholipid Metabolism-Based Prognostic Model Guides Osteosarcoma Therapy
GAS-based stratification not only robustly predicts OS prognosis but also reveals interactions between glycerophospholipid metabolism and tumor immunity, guiding personalized therapeutic strategies and highlighting novel drug candidates for high-risk patients.
Authors
- Donglian Wang (ORCID: https://orcid.org/0000-0002-7075-6888)
- Yong Wen (ORCID: https://orcid.org/0000-0002-1143-3659)
- Jin Zhang (ORCID: https://orcid.org/0000-0002-9117-2793)
- Hongshen Wang (ORCID: https://orcid.org/0000-0002-8712-1432)
- Jian Zhao (ORCID: https://orcid.org/0000-0002-3947-4049)
- Yao Li (ORCID: https://orcid.org/0000-0002-5552-2282)
- Bolai Chen
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Wenzhou Medical University (CN)
- Shanghai Changzheng Hospital (CN)
- Taizhou Municipal Hospital (CN)
- Zhejiang Taizhou Hospital (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2025-10-30
- DOI
- https://doi.org/10.1016/j.tranon.2025.102572
- Citations
- 1
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.94