Analysis of Chemical Constituents of Jiaotai Pill Based on UPLC-Q-Exactive Orbitrap-HRMS Technology and Its Antidiabetic Type 2 Mechanism in Network Pharmacology
Dihydrochelerythrine, a key active component of JTP, may exert antidiabetic effects in T2DM through stable interaction with AKT1, highlighting a potential therapeutic mechanism.
Authors
- Xiuhong Wu (ORCID: https://orcid.org/0000-0002-3236-0145)
- Jubin Zhang
- Jing Liu (ORCID: https://orcid.org/0000-0001-6131-7173)
- Saisai Yang
- Xu Wang (ORCID: https://orcid.org/0000-0002-5700-4876)
- Qiyao Li (ORCID: https://orcid.org/0000-0002-2278-012X)
- Tianjun Liu (ORCID: https://orcid.org/0000-0002-4661-4417)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Heilongjiang University of Chinese Medicine (CN)
- Gansu University of Traditional Chinese Medicine (CN)
- Gansu Provincial Hospital (CN)
Publication Details
- Journal
- Current Pharmaceutical Design
- Published
- 2025-10-28
- DOI
- https://doi.org/10.2174/0113816128402177250911093207
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00