Nephrotoxicity Evaluation of Green and Chemically Synthesized Copper Oxide Nanoparticles in Rats: A Biochemical and Genotoxic Approach
Based on these findings, the biocompatibility of green-synthesized CuO NPs was determined, and they did not induce nephrotoxicity in both parents and their offspring. In contrast, chemically synthesized CuO NPs, when administered at higher concentrations, were found to cause nephrotoxicity, which may also be transmitted to the offspring through lactation.
Authors
- Sania Naz (ORCID: https://orcid.org/0000-0002-8969-7785)
- Salman Alrokayan (ORCID: https://orcid.org/0000-0002-0120-0309)
- Hussain Ali (ORCID: https://orcid.org/0000-0001-6468-3881)
- Muhammad Zia (ORCID: https://orcid.org/0000-0002-4878-6810)
- Ankita Acharya (ORCID: https://orcid.org/0000-0002-8814-5153)
- Tajamul Hussain (ORCID: https://orcid.org/0000-0001-7601-1417)
- Muhammad Latif (ORCID: https://orcid.org/0000-0003-4858-3324)
Institutions
- Veer Kunwar Singh University (IN)
- Quaid-i-Azam University (PK)
- Rawalpindi Medical University (PK)
- University of Balochistan (PK)
- Taibah University (SA)
- King Saud University (SA)
- National Institute of Health (PK)
- Fatima Jinnah Women University (PK)
Publication Details
- Journal
- Current Pharmaceutical Design
- Published
- 2025-10-28
- DOI
- https://doi.org/10.2174/0113816128403424251005233925
- Primary Topic
- Copper-based nanomaterials and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00